This is where Colin's research took an unexpected turn.
He knew the endocannabinoid system was the right target.
It's the system that governs physical ease, mental quiet, and the transition from alert to relaxed. Activate it properly, and you get genuine calm, not suppression, not sedation, not the chemical loan that alcohol takes out against tomorrow morning.
Hemp had always been the obvious candidate.
The plant produces compounds that interact directly with the endocannabinoid system. That's why it became so popular.
But Colin kept running into the same problem: standard hemp supplements produced inconsistent results, required high doses, and still couldn't replicate that reliable, felt-in-the-body shift that people were chasing.
Then he found the reason.
Most hemp manufacturers heat their plant material during processing, a step called decarboxylation that converts the raw compounds the plant naturally makes into something inferior.
It's done out of habit and cost convenience.
And it destroys the most bioavailable form of the plant in the process.
The raw, unheated compounds from hemp are lost.
And according to multiple pharmacokinetics studies, your body absorbs the natural hemp compounds over 500% more effectively than standard heated hemp.
Some studies put the difference even higher.
But the absorption advantage was only part of what caught Colin's attention.
Unheated hemp also interacts with the 5-HT serotonin receptor system, the same pathway involved in the body's natural shift from tension to ease.
Not through suppression.
Not through sedation.
Through the body's own chemistry, properly activated.
That was what people were trying to reach for with a glass of wine. Their body's own wind-down mechanism.
They just didn't have a reliable, clean way to activate it.
Now there was one.