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“I've taken CBD for months and felt basically nothing. Within a week of Natural Dos, I was sleeping through the night.”— Joel S., 57 — Verified Customer
WHY MOST HEMP PRODUCTS DON'T WORK
Most hemp companies use heat to process their product. That converts CBDA into CBD — a far less absorbable compound.
At the same dose, your body absorbs CBDA over 500% better than CBD. That's not marketing — that's pharmacokinetics.
Natural Dos uses a low-temperature purification process that keeps CBDA intact — the way the hemp plant made it.
Formulated by our Doctor and Scientist

Dr. Colin Reily PhD (top) | Dr Luigi F Bertoli MD (bottom)
Formulated by our Doctor and Scientist
Our CBDA products are made with care at every step, from USA grown hemp to cold extraction and purification, to cGMP-compliant manufacturing. Every batch is tested by independent, ISO-accredited third-party laboratories for potency and a broad range of potential contaminants. These testing protocols reflect standards that exceed even what you buy at the grocery store.
View our Labs
SIMPLE. POTENT. BUILT AROUND CBDA.



For adults 21+ · Start with one gummy
Unlike Amazon, you don't even need to return the bottle!
START RISK-FREE →100-day full refund · No questions asked
WHAT CUSTOMERS ARE SAYING
WHY THIS COMPANY EXISTS
Dr. Luigi Bertoli (MD, Johns Hopkins — hematology/oncology) and Dr. Colin Reily (PhD, UAB — molecular pathology) spent years watching patients look for alternatives and coming up empty. Most hemp products on the market delivered inconsistent results because the underlying compound — CBDA — was being destroyed during production. They didn't find a better solution, so they built one.
Colin uses CBDA personally. Luigi recommends it to people in his network.
MEET THE FULL TEAM →HONEST ANSWERS
CBDA is the raw compound the hemp plant naturally produces. CBD is what CBDA becomes when it's heated through a process called decarboxylation. Most hemp companies heat their product during purification, converting CBDA into CBD.
Your body absorbs CBDA over 500% more efficiently than CBD. That's the entire reason most CBD products disappoint people — not because hemp doesn't work, but because they're getting the less bioavailable compound.
No — for the Calm+ Softgels and CBDA Vegan Gummies. Both contain zero THC, confirmed by third-party lab testing. No intoxication, no altered state, no drug-test concern.
The CBDA Gummies with Delta-9 THC do contain a small, precise amount of THC and are intended specifically for sleep. Those are for adults 21+ who want the sleep-support benefit of a low-dose THC + CBDA combination.
Because you were taking a compound with dramatically lower bioavailability. If your CBD was made using heat processing (which describes almost all of it), your body was absorbing a fraction of the dose listed on the label. CBDA doesn't have that problem — the absorption advantage is real and measurable. That's why we built the brand around it.
Stress and anxiety: many customers report noticing a difference within the first few days. Sleep: most within the first week. Physical ease: tends to build over 2–4 weeks. We say give it 30 days to genuinely evaluate it. That's also why the guarantee is 100 days — you have time to actually know.
Yes. Every batch is tested by an independent ISO-certified laboratory for cannabinoid potency, THC content, heavy metals, pesticides, and microbial contamination. Lab results are available on our website.
It depends on the benefit your trying to get and the problems your trying to solve. CLICK HERE to help find what works for you.
You've tried CBD. You deserve to try what the hemp plant actually makes. 100-day guarantee — no risk.
SHOP CBDA — FREE SHIPPING →100-day guarantee · Zero THC options · Ships in 2 business days · Founded by a PhD and an MD