Why is the CBDA supplement field becoming more popular than CBD? Superior absorption leading to high bioavailability is driving high end results.
Natural supplements have been the go-to of many health enthusiasts looking for an alternative route for help with sleep, anxiety, and chronic pain. And CBDA supplements is booming the natural alternative choice for those early consumers who are finding significant benefits.
Many consumers are finding that superior relief with CBDA, which supports the recent pre clinical research studies showing CBDA may have a host of therapeutic effects. These studies indicate anti-inflammatory properties, pain-relieving, and anxiety-reducing effects.
In this blog, we will provide a comprehensive guide on CBDA supplements. We'll also cover what CBDA is, its science and dig deep into its properties. Additionally, we'll guide you in choosing the best CBDA products. We'll help you make an informed decision as you incorporate cannabinoid based therapy into your lifestyle
Article Highlights
- Cannabidiolic acid (CBDA) is among the most abundant cannabinoid in hemp plants.
- CBDA is the raw form of CBD, when CBDA is heated it is converted into CBD through decarboxylation
- CBDA supplements come in various forms, including oils, capsules, and topicals.
- Each form has advantages and disadvantages and will depend on your individual needs and preferences.
- CBDA is over 450% to 1000% better absorbed than CBD, making is a highly potent natural precursor
What is CBDA?
Cannabidiolic acid (CBDA) is the most abundant cannabinoid found in the hemp flower. CBDA is a non-psychoactive compound, and it's a natural precursor to CBD.Like other acidic cannabinoids, CBDA is derived from the moth cannabinoid, cannabigerolic acid (CBGA), from which cannabichromenic acid (CBCA), and tetrahydrocannabinolic acid (THCA) also come from. The CBDA compound is produced when the CBGA molecule is converted via CBDA synthase, similar to THCA or CBCA synthase. Hence, the resulting molecule from a hemp extraction process without heat is CBDA.
Much of the recent research has shown that CBDA and other acidic cannabinoids have significant potential health benefits around:
- Anxiety and stress
- Sleep problems
- Inflammation and chronic pain
- Immune function
- Blood pressure
- Mental state
- Inflammation
- Anxiety and stress
Various research teams are still working to fully understand the therapeutic potential of CBDA and other chemical compounds found in cannabis plants. However, it's good to note that more research is still to support the claims.
Differences Between CBDA and CBD
CBDA is the raw form of CBD, containing a carboxylic group that is unique to all acidic cannabinoids. This unique form means that CBDA is converted into CBD through decarboxylation, which typically occurs during extraction and purification.
One of the main differences between CBDA and CBD, is that CBDA oil is between 450% and 1000% better absorbed than CBD oil.
The Science Behind CBDA
CBDA is a molecule that is structurally similar to CBD and other neutral cannabinoids found in cannabis plants. However, it has a slightly different molecular structure. This difference in chemical composition affects its bioavailability, a term used to define how well a compound gets into the bloodstream.
The ECS is a complex network of receptors and neurotransmitters found both in the central nervous system and in most cells in the body. CBDA interacts with this system by binding preferentially to the CB2 receptors. CBDA is thought to be more potent than CBD, as it has higher bioavailability.
While this is simplified view of CBDA and the ECS, we have written more extensively on this topic in an article on called CBDA and the Endocannabinoid system.
Benefits of CBDA Supplements
CBDA supplements are the next evolution in hemp based alternative medicines. Unlike CBD, CBDA is an acidic cannabinoid that is not limited by poor bioavailability, and exhibits potent alternative therapeutic targets.
Anti inflammatory and pain properties
Multiple studies found that CBDA may have anti-inflammatory effects. This makes it a promising option to treat inflammation and relieve inflammatory pain, such as joint pain. This was through research that where CBDA was found to have potential benefits in suppressing breast cancer metastasis, cancer cell growth, and breast cancer metastasis.
These breast cancer studies conducted by Takeda et al. in 2008 found that CBDA was able to effectively inhibit the spread of highly invasive human breast cancer cells. In 2014, Takeda and his team found that CBDA helped suppress breast cancer cells by inhibiting cyclooxygenase-2 (COX-2), an enzyme known to be involved in inflammatory processes and in the metastasis of cancer cells.
These data on the inhibition of COX2 suggests that CBDA is a potent pain relief option, similar to other over the counter drugs like ibuprofen, but without the side effects. It can possibly work in conjunction with other nonsteroidal anti-inflammatory drugs.
Anxiety and stress
Aside from being a potential alternative in managing chronic pain, it can also relieve anticipatory nausea. Cannabinoids have often been studied for their help with stress and anxiety, and CBDA is no different.
Multiple studies are now showing that CBDA can interact with the 5HT1A serotonin receptor, a common target for anti depression drugs like SSRI (selective serotonin reuptake inhibitors). Along with the known role of the ECS in anxiety, these new properties of CBDA highlight its strong potential treatment for people looking for daily relief.
Anti nausea
Cannabis therapeutics are often used to treat nausea and vomiting in cancer patients. With the discovery that acidic cannabinoids like CBDA may also treat these symptoms, new research areas are being explored. Because of the increased bioavailability of CBDA, doses can be decreased and may still provide superior effects than traditional neutral form cannabinoids.
Choosing the Right CBDA Supplement
CBDA supplements come in various forms, and each form has advantages and disadvantages.- CBDA tinctures - take sublingually under the tongue
- CBDA capsules - easy and discrete
- CBDA edibles - many tasty products exist, but be sure to check the third party tested report since some processes will decarboxylate the CBDA in the edible.
- CBDA creams - works well for specific areas with inflammation or joint discomfort
The type of CBDA product that is best will depend on your individual needs and preferences when choosing the best option.
Check for a certificate of analysis
Consider different factors, such as quality, purity, and potency, when picking out a CBDA product. You should also think about the supplement's form that will work best for you. Consider the administration method and any potential side effects, too. Additionally, it is important to choose a reputable brand. A trustworthy brand uses high-quality, third-party-tested products.
To ensure that you get a high-quality CBDA oil, it is important to do your research. Lastly, it is a good idea to look for certified organic products using only natural, non-GMO ingredients.
Incorporating CBDA Into a Healthy Lifestyle
There are many different ways to incorporate CBDA supplements into your daily routine. You can take CBDA capsules with meals, use a CBDA oil sublingually, or apply a CBDA topical directly to the skin. It is important to choose the form of CBDA that is right for you. Make sure to always follow the recommended dosage instructions.
Consider starting with a lower dose and gradually increasing it over time. This way, you can find the right balance for your body. A typical starting dose is between 20mg and 50mg, but many people take more to get a maximum effect.
Incorporating CBDA supplements into your daily routine can be even more effective when combined with other healthy lifestyle practices. This may include changes to your diet, such as eating a balanced, nutrient-rich diet. Incorporating exercise and mindfulness into your daily routine are also beneficial. Consider other complementary health practices. You can also opt for structured breathing routine or massage therapy to help optimize your overall health and wellness.
Suppose you're ready to incorporate CBDA supplements into your daily routine. It is important to consult with your healthcare provider. Your doctor can guide you with the appropriate dosage and frequency of use. They can discuss with you any potential risks or side effects of using CBDA so you can make an informed decision. They can also help determine if CBDA is a good fit for your health needs and if it will interact with any other medications you may be taking.
Risks and Precautions of CBDA Supplements
CBDA may have potential side effects like any supplement, although these are generally mild and infrequent. Some common side effects of CBDA include:- Upset stomach,
- Dry mouth
- Fatigue
- Drowsiness
- Lightheadedness
More serious side effects may occur in rare cases, and usually only at much higher doses. For this reason, it is important to be aware of these potential risks, start at lower amounts, and seek medical attention if you experience any unusual symptoms.
It is also important to be aware of any potential drug interactions or contraindications when taking CBDA supplements. CBDA may interact with certain medications. These drugs may include but are not limited to blood thinners, antidepressants, and anti-anxiety drugs. Hence, it is important to consult your healthcare provider before starting any new supplement regimen.
Lastly, CBDA may not be appropriate for individuals with certain medical conditions. If you have liver disease, it is important to be aware of any potential contraindications your condition may pose with taking supplements.
Final Thoughts on the Potential Health Benefits of CBDA Supplements
So, are you ready to try CBDA supplements? We hope this article has given you some information on what they are and how they can be used. It's important to know that not all supplements are created equal. Some may have little or no effect at all, while others can be harmful if taken in excess. That's why it's important to choose a CBDA supplement from reputable companies that make high-quality products. Do your research on which brands might be right for you.We may be biased... but Natural Dos has the best Natural Spectrum CBDA oil products on the market. All of our CBDA oil and products are third party tested, and contain all the acidic cannabinoids from the hemp plant that are required for maximum efficacy.